Cisapride Decreases Gastroesophageal Reflux in Preterm Infants

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Cisapride decreases gastroesophageal reflux in preterm infants.

OBJECTIVE Gastrointestinal prokinetic agents, such as cisapride, are commonly used in pediatric practice to improve gastric emptying, to decrease emesis, to improve lower esophageal sphincter tone, and to improve irritability and feeding aversion associated with gastroesophageal reflux (GER). Although cisapride seems to be effective in infants from 2 months to 14 years old, data for younger and...

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Nonpharmacological Management of Gastroesophageal Reflux in Preterm Infants

Gastroesophageal reflux (GOR) is very common among preterm infants, due to several physiological mechanisms. Although GOR should not be usually considered a pathological condition, its therapeutic management still represents a controversial issue among neonatologists; pharmacological overtreatment, often unuseful and potentially harmful, is increasingly widespread. Hence, a stepwise approach, f...

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Pharmacological Therapy of Gastroesophageal Reflux in Preterm Infants

Although gastroesophageal reflux (GER) is a very common phenomenon among preterm infants, its therapeutic management is still an issue of debate among neonatologists. A step-wise approach should be advisable, firstly promoting nonpharmacological interventions and limiting drugs to selected infants unresponsive to the conservative measures or who are suffering from severe GER with clinical compl...

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Gastroesophageal Reflux at Infants

Gastroesophageal reflux is a common sufferance among infants’ specially premature ones. We present a retrospective study over a two years period on newborns and infants admitted at the Childrens’Hospital Braşov for vomiting and regurgitation. We have used modern diagnosing techniques and treatment. Their overall outcome was good.

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Effect of cisapride on the QT interval in infants with gastroesophageal reflux.

OBJECTIVE We prospectively studied the effect of cisapride per se on QT interval in young infants (3-6 months) with gastroesophageal reflux (GER) in a controlled setting. STUDY DESIGN The infants diagnosed with GER and deemed to require therapy with cisapride were divided into 2 groups. Group A comprised infants with GER who underwent an electrocardiogram (ECG) before initiation of therapy wi...

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ژورنال

عنوان ژورنال: PEDIATRICS

سال: 2001

ISSN: 0031-4005,1098-4275

DOI: 10.1542/peds.107.4.e58